The fact that plasma thrombopoietin level of non-CRC T2DM patients was more similar to those of CRC patients than those of control subjects was most likely related to the already known fact that thrombopoietin levels are higher in T2DM [58], but no previous data are available on how similar these values of CRC and T2DM patients should be. Here, THPO is linked to type 2 diabetes mellitus.