In the current study, we observed higher interleukin-6 and thrombopoietin levels of CRC patients, compared to those of control subjects, supporting the presence of paraneoplastic thrombocytosis, which was further strengthened by the result of correlation and survival analysis, in line with earlier findings [1,2,31,32,33,36,37,38]. The gene discussed is THPO; the disease is colorectal carcinoma.