We screened the mRNA level of TRPM2 in the Gene Expression Profiling and Interactive Analysis (GEPIA) and TISIDB databases and found that the expression of TRPM2 was significantly enhanced in several cancers; of these, kidney renal clear cell carcinoma (KIRC) was the most TRPM2-relevant cancer with respect to tumor subtypes, cancer stages, nodal metastasis, and tumor grades. The gene discussed is TRPM2; the disease is neoplasm.