Compared with the control arm, the relative risk of deficiency in the intervention arm was 0.07 (95% CI: 0.03, 0.15) and 0.20 (95% CI: 0.13, 0.30) among WRA and SAC, respectively, against a threshold of Se deficiency defined for the optimal activity of the antioxidant enzyme GPX3. This evidence concerns the gene GPX3 and hyperinsulinemic hypoglycemia, familial, 4.