During the follow-up, 2,521 people were found to have hypertension (HTN), including 1,318 (52.3%) males and 1,203 females (47.7%), 655 had ISH (26.0%), 993 had IDH (39.4%), and 721 had SDH (28.6%) (Figure 2). The gene discussed is ANTXR2; the disease is hypertensive disorder.