To screen the FRGs that would predict OS in ovarian cancer patients, we performed univariate and multivariate Cox regression analyses on the basis of the 60 FRGs.Finally, a 3-gene signature associated with OS was developed, among which HIC1, LPCAT3, and DUOX1 acted as risk factors (HR > 1) in ovarian cancer (Figures 2A,B). Here, DUOX1 is linked to ovarian carcinoma.