The inflammatory markers were higher in sepsis patients compared to ICU controls without sepsis or bacteremia, including white blood count (WBC; 14.9 [9.1–26.5] vs. 9.1 [6.6–13.5] G/L, p = 0.011), C-reactive protein (CRP; 213 [119–309] vs. 12 [4–31] mg/L, p < 0.0001), procalcitonin (PCT; 8.8 [1.2–35.1] vs. 0.2 [0.1–0.3] ng/ml, p < 0.0001), and interleukin-6 (IL-6; 440 [146–1,333] vs. 35 [18–68] pg/mL, p < 0.0001). Here, CRP is linked to bacterial infectious disease with sepsis.