The results of qRT-PCR demonstrated that the mRNA expression levels of ASNS, GPT2, RRM2 in DU-145 PCa cell lines were significantly increased compared with that in RWPE-1 normal prostatic epithelial cells; however, the mRNA expression levels of NFE2L2 in DU-145 PCa cell lines was significantly decreased compared with that in RWPE-1 normal prostatic epithelial cells (Figures 10E–H). The gene discussed is RRM2; the disease is posterior cortical atrophy.