G6PD and G6PD deficiency: G6PD deficiency has been associated to an increased susceptibility to Hepatitis A and E virus infections (Miri-Aliabad et al., 2017; Ahmad et al., 2018), while other studies demonstrated that G6PD-deficient cells supported enterovirus 71 replication more efficiently than control G6PD-expressing cells (Ho et al., 2008).