LAMP1 and infection: In order to evaluate whether this LAMP-deficient environment may also influence the biological behavior of parasites released from these cells, T. cruzi Y strain trypomastigotes collected from a single infection cycle in WT (TcY-WT), LAMP1/2−/− (TcY-L1/2−/−) or LAMP2−/− (TcY-L2−/−) fibroblasts were evaluated concerning their ability to invade L6 myoblasts and WT fibroblasts.