Correlations were observed between increasing expression levels of SRXN1 and KRT6A and an advanced TNM stage (P < 0.001 for both, Figures 4C, D), distant metastasis (P = 0.001 and P < 0.001, respectively, Figures 4E, F), lymph node metastasis (P < 0.001 and P = 0.003, respectively, Figures 4G, H) and smoking (P = 0.001 and P = 0.03, respectively, Figures 4I, J). This evidence concerns the gene SRXN1 and metastatic malignant neoplasm in the lymph nodes.