The TMB of the ZCCHC17 high expression group was also significantly higher than that of the low expression group (Figure 7D); the results of the chi-square test showed that the proportion of patients with TP53 mutation in HCC patients in the ZCCHC17 high expression group was also significantly higher than that of the ZCCHC17 low expression group (Figure 7E). Here, TP53 is linked to hepatocellular carcinoma.