AKT1 and neoplasm: The tumor growth and development mechanisms involved in miR-1301 include at least 6 classical signaling pathways, including the Wnt/β-catenin signaling pathway (3, 19, 28, 45), p53 signaling pathway (35, 49), mTOR signaling pathway (33), Ras signaling pathway (24), NF-κB signaling pathway (11), and PI3K/AKT signaling pathway (17, 20, 26) (Figures 4 and 5, Table 3).