RP11 can trigger the migration, invasion, and EMT of colorectal cancer cells by promoting the post-translational up-regulation of the EMT transcription factor (EMT-TF) Zeb1 (70); The RNA-binding protein RALY (also known as hnRNPCL2) enhances the m6A modification of a subset of miRNAs (miR-483, miR-676, and miR-877) through METTL3, which promotes the post-transcriptional processing of a subset of miRNAs. Here, METTL3 is linked to colorectal cancer.