KCNK15-AS1 and ALKBH5 can inhibit EMT, thereby inhibiting the migration and invasion of pancreatic cancer cells (101); In pancreatic cancer, IGF2BP2 as a reader recognizes m6A-modified lncRNA DANCR, thereby improving the stability of DANCR, and ultimately promoting tumorigenesis, cell proliferation and stem cell-like properties of pancreatic cancer (71); The study found that rs7495 (SNP) in the 3’UTR of HNRNPC may destroy its binding site with has-miR-183-3p, thereby increasing the expression of HNRNPC and promoting the proliferation of PDAC cells (102);. This evidence concerns the gene HNRNPC and familial pancreatic carcinoma.