LINRIS blocks the degradation of Reader IGF2BP2 through the ubiquitination-autophagy pathway, thereby maintaining the stability of MYC mRNA (MYC mRNA is a typical target of IGF2BP2 and one of the core regulators of glycolysis) and promotes MYC-mediated Glycolysis and proliferation of colorectal cancer cells. This evidence concerns the gene LINC00920 and colorectal cancer.