CircDLC1 can bind to the RNA-binding protein Hur and reduce the interaction between Hur and MMP1 mRNA, thereby inhibiting the expression of MMP1 and ultimately inhibiting the progression of HCC (95); LncRNA GATA3-AS, transcribed from the antisense chain of GATA3 gene, specifically promotes the m6A modification of the tumor suppressor GATA3 precursor mRNA (pre-mRNA) by methyltransferase KIAA1429, which reduces the stability of GATA3 pre-mRNA. The gene discussed is VIRMA; the disease is hepatocellular carcinoma.