CD4 and HIV infectious disease: In Nepal, cotrimoxazole prophylaxis is given to HIV-infected adults with a CD4 count of <500 cells/μl, adults who have had an episode of Pneumocystis carinii pneumonia and individuals with symptomatic HIV infection [47].Comorbidities in PLHIV attending the ART center and people were not assessed in this study, and all the subjects were screened only once for S. aureus or MRSA colonization.