Glucose transporter 1 (GLUT-1), sodium glucose junction transporter (SGLT), and monocarboxylic acid transporter 1 (MCT1) levels are all elevated in ccRCC tumors, and GLUT-1 is regulated by HIF-1α and increases glucose uptake 10. The gene discussed is SLC2A1; the disease is nonpapillary renal cell carcinoma.