The results illustrated that E2F2 expression had extensively correlation with immune infiltrates, inculding Th2 cells, T17 cells, T helper cells, Tgd, Tcm, aDC, pDC, NK cells, NK CD56dim cells, cytotoxic cells, B cells, macrophages and mast cells, and these cells play a critical role in cancer control. The gene discussed is E2F2; the disease is cancer.