Through analyzing the correlation between E2F2 and 24 immune-cell subsets in CRC by means of ssGSEA with Spearman r (Figure 6A), we found that E2F2 was positively correlated with infiltration levels of Th2 cells (R = 0.380, p < 0.001, Figure 6B), aDC (R = 0.200, p < 0.001, Figure 6C), Th17 cells (R = 0.180, P < 0.001, Figure 6D), NK CD56dim cells (R = 0.140, p < 0.001, Figure 6E), T helper cells (R = 0.130, p = 0.001, Figure 6F), cytotoxic cells (R = 0.120, p = 0.002, data not shown) and B cells (R = 0.089, p = 0.023, data not shown). The gene discussed is E2F2; the disease is colorectal carcinoma.