POU4F3 and cancer: Considering the overall low expression of POU4F3 in cancer tissues, we divided LUAD patients into the POU4F3-high (≥2) and POU4F3-low (<2) groups according to the median IHC score of POU4F3 expression in LUAD tissues, and we did so in order to evaluate the relationship between POU4F3 expression and clinicopathological characteristics.