To visualize the impact of SRSF9 on prognosis in pan-cancer, Kaplan–Meier plotter was employed and it unfolded that overexpression of SRSF9 had a significant association with poorer overall survival in HNSC, KIRC, LIHC, LUAD, and SARC, and reversely in ESCA, OV, THYM, and UCEC. Here, SRSF9 is linked to cancer.