Cox proportional hazard model analysis showed that high SRSF9 expression was associated with unfavorable outcomes in ACC (HR = 2.705, p=0.002), KIRC (HR = 1.925, p=0.005), LGG (HR = 2.133, p < 0.001), LIHC (HR = 1.405, p=0.005), PRAD (HR = 2.886, p=0.001), and UVM (HR = 7.488, p < 0.001), but with optimistic prognosis in OV (HR = 0.778, p=0.040). The gene discussed is SRSF9; the disease is adrenal cortex carcinoma.