NLRP2, NLRP7, and PLCG1 were the only gene alterations in LGG, and NLRP3, NLRP7, NLRP2, SCAF11, NOD1, PLCG1, NLRP1, and CASP1 were gene alterations in GBM. This evidence concerns the gene NLRP3 and glioblastoma.