The Kaplan-Meier plot indicated that high expression of CASP3, CASP4, CASP5, CASP6, CASP8, ELANE, GSMAD, IL6, NLRP3, NOD1, NOD2, PLCG1, PRKACA, PYCARD, and SCAF11 was associated with poorer OS in glioma. Here, CASP5 is linked to central nervous system cancer.