For Blimp-1+ eTregs in the CNS of experimental autoimmune encephalitis-diseased animals it was elucidated that Blimp-1, here maintained by proinflammatory STAT-1 signaling, ensures Foxp3 expression by inhibition of the methyltransferase Dnmt3a (16). The gene discussed is PRDM1; the disease is autoimmune encephalitis.