CD4 and myeloid sarcoma: The pathomechanisms of MS involve autoreactive CD4+ T cells with specificity for myelin- and a few other proteins and peptides thereof (4, 12–14), proinflammatory B cells (15) and possibly also autoantibodies (16), but likely also other cell types including CD8+ T cells (17), microglia and other innate immune cells (18).