TP53 and hepatocellular carcinoma: As presented in Figure 5E, several pathways including “p53 signaling pathway”, “microRNAs in cancer”, “hepatocellular carcinoma”, “apoptosis”, “DNA replication” and “cell cycle” were revealed as the most significantly enriched KEGG pathways, indicating that PHF19 was crucially involved in the development and progression of cancers, especially HCC.