IFIH1 and interstitial lung disease: The anti-melanoma differentiation-associated gene 5 (MDA5) antibody, which is an MSA, was first reported to be an anti-clinically amyopathic dermatomyositis-140 (anti-CADM-140) antibody specific to CADM in a Japanese cohort in 2005, which showed a strong association with rapidly progressive interstitial lung disease (ILD) (3).