Firstly, survival analysis in 88 NPC patients with PFS data from GSE102349 indicated that METTL3 and YTHDF3 were protective factors while 9 m6A regulators (ALKBH5, HNRNPA2B1, LRPPRC, YTHDF1, THDF2, IGF2BP1, RBMX, CBLL1, and ELAVL1) were risk factors for PFS (Figure 2A). The gene discussed is METTL3; the disease is nasopharyngeal carcinoma.