In addition, compared with mice in the rAAV.sc group, mice treated with rAAV.shTLR7 exhibited reduced production of the pathogenic uveitis cytokines IFN-γ and IL-17 by splenocytes in response to IRBP (Figure 6E), although no significant difference was found in the production of IL-10 (Figure 6F) or Treg frequency (Figure 6G). This evidence concerns the gene IL17A and uveitis.