LCK and cancer: We found that: (i) the correlation levels for both CD20 and LCK were varying across different cancer and tissue types (Figures 2A and S7A); (ii) in both the pan-cancer and pan-tissue analyses, the associations were significant in LCK but insignificant in CD20 (Figures 2B and S7B); (iii) the correlation levels for CD20 were very low in 93.8% of the cancer types and 91.3% of the tissue types (Figures 2A and S7A; Spearman rho < 0.3); by contrast, the low correlation levels for LCK were observed in 12.5% of cancer types and 60.9% of tissue types.