In the gender-related differences, males had significantly lower LCK protein levels than females in the lung squamous cell carcinoma (LUSC), breast invasive carcinoma (BRCA), and bladder urothelial carcinoma (BLCA), and males had significantly higher CD20 protein levels in the LUSC, esophageal carcinoma (ESCA) and glioblastoma multiforme (GBM) (Figure S9). The gene discussed is LCK; the disease is invasive breast carcinoma.