F10 and Renal insufficiency: When the time from the last intake is less than 48 h or is unknown or in situations of renal insufficiency, the strategy will depend on the NOAC considered with the option of an immediate reversion by idarucizumab in patients on dabigatran or the previous assessment of anticoagulant activity in patients on factor-Xa inhibitors or when idarucizumab is unavailable.