PTX3 and age-related macular degeneration: So far, no large study has been conducted to assess associations between the ocular levels of PTX3 and AMD, however, in small cohorts of donors; trends of increasing protein concentration in the vitreous (Stravalaci et al., 2020) and staining intensity in the choriocapillaris (Swinkels et al., 2018) have been documented in AMD subjects.