PTX3 and age-related macular degeneration: Using fluorescence microscopy techniques, we have afterward recapitulated these findings in an independent cohorts of AMD donors, and demonstrated that PTX3 is expressed in the eye of non-AMD donors too, where it localizes at the interface between the RPE and choroid, particularly in the intercapillary septa of the choriocapillaris (Swinkels et al., 2018).