Huaxian Decoction is a classic prescription for the treatment of pulmonary fibrosis, which is anti-inflammatory effect may be mediated by inhibition of inflammatory factor TNF-α、TGF-β, and inhibit NF-κB activation of inflammatory signaling pathways, thus effectively alleviate inflammatory reaction, reduce clinical symptoms, improve lung function, and reduce the levels of serum laminin, hyaluronic acid and other pulmonary fibrosis indicators (Chen et al., 2016; Gan et al., 2020). This evidence concerns the gene TNF and pulmonary fibrosis.