Baill (Wang et al., 2016), phenol, flavonoid, and sugar collected in the fruit of Abelmoschus esculentus (Zhang et al., 2020b), and total glycosides, isolated from Ligustrum lucidum L. Moench (Zhao and Liu, 2020), have the potency to downregulate LXRα and a set of associated genes, indicating both preventive and therapeutic role in regard to metabolic disorders. This evidence concerns the gene NR1H3 and metabolic disease.