, proved to ameliorate P2X7 receptor-mediated NLRP3 (nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing 3) inflammasome and hepatic fibrosis through inducing LXRα/β pathway in the development of thioacetamide-stimulated hepatic fibrosis mice (Han et al., 2018). This evidence concerns the gene P2RX7 and Hepatic fibrosis.