SLC12A5 and epilepsy: It is to note that decreased GABA level in astrocytes produces decreased tonic inhibition not only in epilepsy (but be aware of the altered activity of KCC2 in epilepsy; di Cristo et al., 2018), but also in a mouse model for attention-deficit/hyperactivity disorder (Kim et al., 2017) and Huntington disease (Wójtowicz et al., 2013).