IFNA1 and viral infectious disease: Among them, type I IFNs play an important role in promoting host defense against virus infections, including IFN-α, IFN-β, IFN-ε, IFN-ω, IFN-κ, IFN-δ, IFN-τ, and IFN-ζ, in particular IFN-α, and IFN-ω, with potent immunomodulatory, antiviral, and antiproliferative properties [7].