In addition, PBX3 can also mediate the inhibitory role of some miRNAs, such as miR‐509‐3P, miR‐144‐3p, miR‐320a and miR‐526b, on EMT in a variety of cancer types, including PCa, GC and melanoma.59, 86, 89 EMT has been shown to be engaged in multiple steps of the metastasis process. Here, PBX3 is linked to melanoma.