In this study (78), ferroptosis was classified based on histopathological hallmarks of ferroptosis, such as the accumulation of lipid peroxidation products (4HNE, MDA) and lipid droplet formation with oil red O staining; mitochondrial anomalies and the accumulation of lipid droplet structures by transmission electron microscopy; gene expression changes by RNA sequencing on laser capture micro-dissected tumor sections; and the absence of tumor-specific cleaved caspase 3. The gene discussed is CASP3; the disease is neoplasm.