Using large scale whole transcriptome RNA sequencing data obtained from The Cancer Genome Atlas (TCGA) for 242 prostate adenocarcinoma (PRAD) patients from the United States and Germany, a recent study [50] found specific microbes such as Listeria monocytogenes, Methylobacterium radiotolerans JCM 2831, and Xanthomonas albilineans GPE PC73 to be negatively correlated with Gleason score, Tumor-Node-Metastasis (TNM) stage, and prostate-specific antigen (PSA) level, respectively. This evidence concerns the gene KLK3 and prostate adenocarcinoma.