When dichotomizing the 13 proteins for which ≥500 individuals had values below LOD into less than and greater than or equal to LOD, tumour necrosis factor (TNF) was associated with a higher risk of pancreatic cancer [HR = 2.36, 95% CI (1.31, 4.25); P = 0.0043]. This evidence concerns the gene TNF and pancreatic neoplasm.