In RA patients, ITIH4 was negatively related to CRP (rs = −0.358, p < 0.001) and DAS28‐ESR (rs = −0.253, p = 0.014), while ITIH4 was not correlated with age (rs = 0.131, p = 0.209), gender (Z = −0.900, p = 0.368), body mass index (BMI) (rs = −0.122, p = 0.245), disease duration (rs = −0.075, p = 0.477), RF (Z = −0.657, p = 0.511), ACPA (Z = −1.680, p = 0.093), TJC (rs = −0.199, p = 0.056), SJC (rs = −0.138, p = 0.188), ESR (rs = −0.186, p = 0.074), or HAQ‐DI score (rs = −0.157, p = 0.132) (Figure 2A‐L). Here, CRP is linked to rheumatoid arthritis.