ZC3H15 and gastric cancer: To further confirm the functional role of ZC3H15 in cell proliferation and metastasis of GC cells, we overexpressed ZC3H15 in ZC3H15-knockdown (shZC3H15#2) cells, in which ZC3H15 mRNA and protein expression levels returned to those in HGC-27 and MKN-45 cells (Fig. 3A, B).