In contrast, the high expression of the 17 genes (EGFR (211550_at), ACVR2A (205327_s_at), CAV1 (203065_s_at), FAT4 (219427_at), ID1 (208937_s_at), ID4 (209292_at), KIT (205051_s_at), LEPR (207255_at), MET (213816_s_at), NRG1 (208241_at), PPARG (208510_s_at), PRDM16 (220928_s_at), PREX2 (220732_at), PROX1 (207401_at), RYR3 (206306_at), SOX17 (219993_at), and STAT5A (203010_at)) could significantly improve the prognosis of breast cancer patients. The gene discussed is LEPR; the disease is breast cancer.