Inhibitors of these regulators, like DNA methylation inhibitor 5-azacytidine (5-aza) [89] and histone acetyltransferase EP300 inhibitor C646 [108], as well as miRNA miR-193a-3p mimic [78, 149] are able to indirectly or directly suppress ALKBH5 expression in cancer cells (Fig. 5d). Here, ALKBH5 is linked to cancer.