Yang et al. [23] recruited 190 NSHL patients, and after excluding the common GJB2, SLC26A4 and MT-RNR1 variants, 33 probands were determined to have rare HL variants, 28 were autosomal recessive, four were autosomal dominant, and one was mitochondrial. The gene discussed is GJB2; the disease is nodular sclerosis classical Hodgkin lymphoma.