NFKB1 and hepatocellular carcinoma: Similar mechanisms were also involved in AURKA-mediated radioresistance, with Shen et al. [24] revealing that upregulation of AURKA reduced radiotherapy-induced apoptosis in human HCC cells through the activation of NF-κB signaling, and that knockdown of AURKA resensitized radioresistant HCC cells to radiotherapy.