COL2A1 and achondrogenesis type II: Among these novel candidate genes (reported for the first time in this study), collagen type II alpha 1 chain (COL2A1), located in an extreme genomic region of an unassembled scaffold (Un0251) in the Dwarf Lop breed, has been reported to cause a wide spectrum of skeletal disorders in mammals, including achondrogenesis type II in humans [51–53] and the bulldog-type dwarfism in cattle [54–58].