PSMD1 and infection: From multiple sequence alignment, the mAbA3-epitope is shared by both G1 and G2 PEDV strains and other alphacoronaviruses, including canine- and feline-coronaviruses and porcine transmissible gastroenteritis virus (TGEV), indicating that this region of the S1 protein is highly conserved and could be indispensable for alphacoronaviruses during initial infection.