GPT and fibrosis: In the univariable analysis BMI ≥ 25 kg/m2, infection with GT3, fibrosis F4 corresponding to liver cirrhosis, decompensation of liver function at baseline (B or C in CP scale), documented esophageal varices, concomitant diabetes, previous ineffective treatment, baseline ALT activity > 70 U/L, higher bilirubin concentration, and lower albumin level and platelet count were negative predictors of an SVR (Table 6).