Recently it has been described that miR-124 expression in the CNS decreases as COVID-19 becomes more severe [145], thus proving it to be an essential regulator in the CNS, in addition to being a regulator of the immune system at this level and an important modulator of epileptic states by directly targeting multiple components of the TLR signaling cascade, including TLR6, myeloid differentiation factor 88 (MyD88), TRAF6, and TNF-α [126,127,146,147]. This evidence concerns the gene TNF and COVID-19.