“PI3K/AKT” and “Integrin signalling” were significant in IPA of the IA-H/S data set (S4 File) and several infection-associated genes involved in integrin signalling, possess differences in the number of TashAT2 binding motifs between the two genomes (LAMC1, ACTA2, ITGA4 and ITGB5). The gene discussed is ITGB5; the disease is infection.