We identified changes in the splicing of general transcription factor II H subunit 1 and 2c (GTF2H1 and GTF2H2C), Fanconi anemia group a and g (FANCA and FANCG), and checkpoint kinase 1 and 2 (CHEK1 and CHEK2) (Fig. 4F and fig. The gene discussed is CHEK1; the disease is Fanconi anemia.