Comparison of SF3B1 and USP7 protein levels in T-ALL and other hematological (B-ALL and myeloid subtypes) and solid tumors (lung, breast, melanoma, and pancreatic adenocarcinomas) showed relatively high levels of SF3B1 and USP7 in leukemia cells compared to solid cancer cells (fig. This evidence concerns the gene SF3B1 and acute lymphoblastic leukemia.