We removed the METTL7A, RAB31, PPP2R1B, PRDM1, HIST1H1B, AKAP2, SFRS2 and RAC3 genes from our candidate list because the expression trends of these genes in AD were the same as in our two types of omics data (Fig. 1B, all red or all blue boxes in the three databases). The gene discussed is RAC3; the disease is Alzheimer disease.