Phosphorylated EGFR (p-EGFR) activates cell signaling pathways and has implications in cell cycle, apoptosis, angiogenesis, and cell proliferation.[11,12] It has been shown that EGFR and p-EGFR are esstential in the carcinogenesis and development of nasopharyngeal carcinoma. The gene discussed is EGFR; the disease is nasopharyngeal carcinoma.